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The ER stress sensor inositol-requiring enzyme 1α in Kupffer cells promotes hepatic ischemia-reperfusion injury

Hepatic ischemia/reperfusion (I/R) injury is an inflammation-mediated process arising from ischemia/reperfusion-elicited stress in multiple cell types, causing liver damage during surgical procedures and often resulting in liver failure. Endoplasmic reticulum (ER) stress triggers the activation of t...

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Detalles Bibliográficos
Autores principales: Cai, Jie, Zhang, Xiaoge, Chen, Peng, Li, Yang, Liu, Songzi, Liu, Qian, Zhang, Hanyong, Wu, Zhuyin, Song, Ke, Liu, Jianmiao, Shan, Bo, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760522/
https://www.ncbi.nlm.nih.gov/pubmed/34953853
http://dx.doi.org/10.1016/j.jbc.2021.101532