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A common human missense mutation of vesicle coat protein SEC23B leads to growth restriction and chronic pancreatitis in mice

SEC23B is one of two vertebrate paralogs of SEC23, a key component of the coat protein complex II vesicles. Complete deficiency of SEC23B in mice leads to perinatal death caused by massive degeneration of professional secretory tissues. However, functions of SEC23B in postnatal mice and outside prof...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Liu, Zhigang, Zhang, Chao, Khoriaty, Rami, Zhu, Min, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760524/
https://www.ncbi.nlm.nih.gov/pubmed/34954140
http://dx.doi.org/10.1016/j.jbc.2021.101536