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A common human missense mutation of vesicle coat protein SEC23B leads to growth restriction and chronic pancreatitis in mice
SEC23B is one of two vertebrate paralogs of SEC23, a key component of the coat protein complex II vesicles. Complete deficiency of SEC23B in mice leads to perinatal death caused by massive degeneration of professional secretory tissues. However, functions of SEC23B in postnatal mice and outside prof...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760524/ https://www.ncbi.nlm.nih.gov/pubmed/34954140 http://dx.doi.org/10.1016/j.jbc.2021.101536 |