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Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin

Keyhole limpet hemocyanin (KLH) is a glycosylated multi-subunit metalloprotein that elicits a strong nonspecific immune activation, thus inducing both cellular and humoral immune responses. The exceptional immunogenicity of this protein can be leveraged to vaccinate mice against self-antigens that o...

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Detalles Bibliográficos
Autores principales: Montégut, Léa, Chen, Hui, Bravo-San Pedro, José Manuel, Motiño, Omar, Martins, Isabelle, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760546/
https://www.ncbi.nlm.nih.gov/pubmed/35059656
http://dx.doi.org/10.1016/j.xpro.2021.101095