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Immunization of mice with the self-peptide ACBP coupled to keyhole limpet hemocyanin
Keyhole limpet hemocyanin (KLH) is a glycosylated multi-subunit metalloprotein that elicits a strong nonspecific immune activation, thus inducing both cellular and humoral immune responses. The exceptional immunogenicity of this protein can be leveraged to vaccinate mice against self-antigens that o...
Autores principales: | Montégut, Léa, Chen, Hui, Bravo-San Pedro, José Manuel, Motiño, Omar, Martins, Isabelle, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760546/ https://www.ncbi.nlm.nih.gov/pubmed/35059656 http://dx.doi.org/10.1016/j.xpro.2021.101095 |
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