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A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing

BACKGROUND: miRNAs are regulatory transcripts established as repressors of mRNA stability and translation that have been functionally implicated in carcinogenesis. miR-10b is one of the key onco-miRs associated with multiple forms of cancer. Malignant gliomas exhibit particularly striking dependence...

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Detalles Bibliográficos
Autores principales: El Fatimy, Rachid, Zhang, Yanhong, Deforzh, Evgeny, Ramadas, Mahalakshmi, Saravanan, Harini, Wei, Zhiyun, Rabinovsky, Rosalia, Teplyuk, Nadiya M., Uhlmann, Erik J., Krichevsky, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760648/
https://www.ncbi.nlm.nih.gov/pubmed/35033060
http://dx.doi.org/10.1186/s12943-022-01494-z