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A nuclear function for an oncogenic microRNA as a modulator of snRNA and splicing
BACKGROUND: miRNAs are regulatory transcripts established as repressors of mRNA stability and translation that have been functionally implicated in carcinogenesis. miR-10b is one of the key onco-miRs associated with multiple forms of cancer. Malignant gliomas exhibit particularly striking dependence...
Autores principales: | El Fatimy, Rachid, Zhang, Yanhong, Deforzh, Evgeny, Ramadas, Mahalakshmi, Saravanan, Harini, Wei, Zhiyun, Rabinovsky, Rosalia, Teplyuk, Nadiya M., Uhlmann, Erik J., Krichevsky, Anna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760648/ https://www.ncbi.nlm.nih.gov/pubmed/35033060 http://dx.doi.org/10.1186/s12943-022-01494-z |
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