Long-term in vivo application of a potassium channel-based optogenetic silencer in the healthy and epileptic mouse hippocampus

BACKGROUND: Optogenetic tools allow precise manipulation of neuronal activity via genetically encoded light-sensitive proteins. Currently available optogenetic inhibitors are not suitable for prolonged use due to short-lasting photocurrents, tissue heating, and unintended changes in ion distribution...

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Detalles Bibliográficos
Autores principales: Kleis, P., Paschen, E., Häussler, U., Bernal Sierra, Y. A., Haas, C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760681/
https://www.ncbi.nlm.nih.gov/pubmed/35031048
http://dx.doi.org/10.1186/s12915-021-01210-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760681/
https://www.ncbi.nlm.nih.gov/pubmed/35031048
http://dx.doi.org/10.1186/s12915-021-01210-1

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