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Engineered adipose-derived stem cells with IGF-1-modified mRNA ameliorates osteoarthritis development
BACKGROUND: Osteoarthritis (OA), a prevalent degenerative disease characterized by degradation of extracellular matrix (ECM), still lacks effective disease-modifying therapy. Mesenchymal stem cells (MSCs) transplantation has been regarded as the most promising approach for OA treatment while engraft...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760691/ https://www.ncbi.nlm.nih.gov/pubmed/35033199 http://dx.doi.org/10.1186/s13287-021-02695-x |