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Engineered adipose-derived stem cells with IGF-1-modified mRNA ameliorates osteoarthritis development

BACKGROUND: Osteoarthritis (OA), a prevalent degenerative disease characterized by degradation of extracellular matrix (ECM), still lacks effective disease-modifying therapy. Mesenchymal stem cells (MSCs) transplantation has been regarded as the most promising approach for OA treatment while engraft...

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Detalles Bibliográficos
Autores principales:	Wu, Haoyu, Peng, Zhi, Xu, Ying, Sheng, Zixuan, Liu, Yanshan, Liao, Youguo, Wang, Yin, Wen, Ya, Yi, Junzhi, Xie, Chang, Chen, Xuri, Hu, Jiajie, Yan, Bingqian, Wang, Huijing, Yao, Xudong, Fu, Wei, Ouyang, Hongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760691/ https://www.ncbi.nlm.nih.gov/pubmed/35033199 http://dx.doi.org/10.1186/s13287-021-02695-x

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