Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis

BACKGROUND: The development of lethal cancer metastasis depends on the dynamic interactions between cancer cells and the tumor microenvironment, both of which are embedded in the extracellular matrix (ECM). The acquisition of resistance to detachment-induced apoptosis, also known as anoikis, is a cr...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Li, Yun, Liu, Hua, Zhang, Jiahui, Wang, Jie, Xia, Jia, Zhang, Yu, Yu, Xiang, Ma, Jinyan, Huang, Masha, Wang, Jiahui, Wang, Liangzhe, Li, Qian, Cui, Rutao, Yang, Wen, Xu, Yingjie, Feng, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760697/
https://www.ncbi.nlm.nih.gov/pubmed/35033172
http://dx.doi.org/10.1186/s13046-022-02242-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760697/
https://www.ncbi.nlm.nih.gov/pubmed/35033172
http://dx.doi.org/10.1186/s13046-022-02242-3

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