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Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover

BACKGROUND: Prostate cancer growth is driven by androgen receptor signaling, and advanced disease is initially treatable by depleting circulating androgens. However, prostate cancer cells inevitably adapt, resulting in disease relapse with incurable castrate-resistant prostate cancer. Androgen depri...

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Detalles Bibliográficos
Autores principales: Raftopulos, Nikki L., Washaya, Tinashe C., Niederprüm, Andreas, Egert, Antonia, Hakeem-Sanni, Mariam F., Varney, Bianca, Aishah, Atqiya, Georgieva, Mariya L., Olsson, Ellinor, dos Santos, Diandra Z., Nassar, Zeyad D., Cochran, Blake J., Nagarajan, Shilpa R., Kakani, Meghna S., Hastings, Jordan F., Croucher, David R., Rye, Kerry-Anne, Butler, Lisa M., Grewal, Thomas, Hoy, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760736/
https://www.ncbi.nlm.nih.gov/pubmed/35033184
http://dx.doi.org/10.1186/s40170-021-00278-1