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GDF11 alleviates neointimal hyperplasia in a rat model of artery injury by regulating endothelial NLRP3 inflammasome activation and rapid re-endothelialization

BACKGROUND: Neointimal hyperplasia induced by interventional surgery can lead to progressive obliteration of the vascular lumen, which has become a major factor affecting prognosis. The rate of re-endothelialization is known to be inversely related to neointima formation. Growth differentiation fact...

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Detalles Bibliográficos
Autores principales: Li, Lei, Gao, Yan, Liu, Zhenchuan, Dong, Chenglai, Wang, Wenli, Wu, Kaiqin, Gu, Shaorui, Zhou, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760779/
https://www.ncbi.nlm.nih.gov/pubmed/35033112
http://dx.doi.org/10.1186/s12967-022-03229-6