Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway

The mechanisms of chronic intermittent hypoxia (CIH)-induced cognitive deficits remain unclear. Here, our study found that about 3 months CIH treatment induced lipid droplets (LDs) accumulation in hippocampal nerve and glia cells of C57BL/6 mice, and caused severe neuro damage including neuron lesio...

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Detalles Bibliográficos
Autores principales: Li, Dongze, Xu, Na, Hou, Yanyan, Ren, Wenjing, Zhang, Na, Wang, Xi, Sun, Yeying, Lu, Wenxue, Qu, Guiwu, Yu, Yan, Lv, Changjun, Han, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760803/
https://www.ncbi.nlm.nih.gov/pubmed/35030992
http://dx.doi.org/10.1186/s10020-021-00427-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760803/
https://www.ncbi.nlm.nih.gov/pubmed/35030992
http://dx.doi.org/10.1186/s10020-021-00427-8

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