Anti-high-mobility group box-1 (HMGB1) mediates the apoptosis of alveolar epithelial cells (AEC) by receptor of advanced glycation end-products (RAGE)/c-Jun N-terminal kinase (JNK) pathway in the rats of crush injuries

OBJECTIVES: The lung injury is often secondary to severe trauma. In the model of crush syndrome, there may be secondary lung injury. We hypothesize that high-mobility group box 1 (HMGB1), released from muscle tissue, mediates the apoptosis of alveolar epithelial cells (AEC) via HMGB1/Receptor of adv...

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Detalles Bibliográficos
Autores principales: Zhang, Bin-Fei, Song, Wei, Wang, Jun, Wen, Peng-Fei, Zhang, Yu-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760810/
https://www.ncbi.nlm.nih.gov/pubmed/35033142
http://dx.doi.org/10.1186/s13018-021-02903-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760810/
https://www.ncbi.nlm.nih.gov/pubmed/35033142
http://dx.doi.org/10.1186/s13018-021-02903-7

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