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Recombinant production of the lantibiotic nisin using Corynebacterium glutamicum in a two-step process

BACKGROUND: The bacteriocin nisin is naturally produced by Lactococcus lactis as an inactive prepeptide that is modified posttranslationally resulting in five (methyl-)lanthionine rings characteristic for class Ia bacteriocins. Export and proteolytic cleavage of the leader peptide results in release...

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Detalles Bibliográficos
Autores principales: Weixler, Dominik, Berghoff, Max, Ovchinnikov, Kirill V., Reich, Sebastian, Goldbeck, Oliver, Seibold, Gerd M., Wittmann, Christoph, Bar, Nadav S., Eikmanns, Bernhard J., Diep, Dzung B., Riedel, Christian U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760817/
https://www.ncbi.nlm.nih.gov/pubmed/35033086
http://dx.doi.org/10.1186/s12934-022-01739-y