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A Mutation–Selection Model of Protein Evolution under Persistent Positive Selection

We use first principles of population genetics to model the evolution of proteins under persistent positive selection (PPS). PPS may occur when organisms are subjected to persistent environmental change, during adaptive radiations, or in host–pathogen interactions. Our mutation–selection model indic...

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Detalles Bibliográficos
Autores principales: Tamuri, Asif U, dos Reis, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760937/
https://www.ncbi.nlm.nih.gov/pubmed/34694387
http://dx.doi.org/10.1093/molbev/msab309