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Phylogenetic Articulation of Uric Acid Evolution in Mammals and How It Informs a Therapeutic Uricase
The role of uric acid during primate evolution has remained elusive ever since it was discovered over 100 years ago that humans have unusually high levels of the small molecule in our serum. It has been difficult to generate a neutral or adaptive explanation in part because the uricase enzyme evolve...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760943/ https://www.ncbi.nlm.nih.gov/pubmed/34718698 http://dx.doi.org/10.1093/molbev/msab312 |