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Development and in vivo Evaluation of Hydroxy-α-Sanshool Intranasal Liposomes as a Potential Remedial Treatment for Alzheimer’s Disease

PURPOSE: Hydroxy-α-sanshool (HAS) improves cognitive dysfunction, but its structural instability has limited its clinical application. The present study was conducted to investigate the optimal formulation of hydroxy-α-sanshool liposomes (HAS-LPs) and its effect on ameliorating learning and memory d...

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Detalles Bibliográficos
Autores principales: Li, Ruolan, Lu, Feng, Sun, Xue, He, Liying, Duan, HuXinyue, Peng, Wei, Wu, ChunJie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761002/
https://www.ncbi.nlm.nih.gov/pubmed/35046654
http://dx.doi.org/10.2147/IJN.S339979