Physiological clearance of Aβ by spleen and splenectomy aggravates Alzheimer‐type pathogenesis

BACKGROUND: A previous study demonstrated that nearly 40%–60% of brain Aβ flows out into the peripheral system for clearance. However, where and how circulating Aβ is cleared in the periphery remains unclear. The spleen acts as a blood filter and an immune organ. The aim of the present study was to...

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Detalles Bibliográficos
Autores principales: Yu, Zhong‐Yuan, Chen, Dong‐Wan, Tan, Cheng‐Rong, Zeng, Gui‐Hua, He, Chen‐Yang, Wang, Jun, Bu, Xian‐Le, Wang, Yan‐Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761003/
https://www.ncbi.nlm.nih.gov/pubmed/34939734
http://dx.doi.org/10.1111/acel.13533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761003/
https://www.ncbi.nlm.nih.gov/pubmed/34939734
http://dx.doi.org/10.1111/acel.13533

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