Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging

DNA methylation alterations play mechanistic roles in aging; however, the epigenetic regulators/mediators causally involved in renal aging remain elusive. Here, we report that natural and D‐galactose (D‐gal)‐induced aging kidneys display marked suppression of antiaging factor NRF2 (nuclear factor er...

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Detalles Bibliográficos
Autores principales: Gao, Qi, Chen, Fang, Zhang, Lijun, Wei, Ai, Wang, Yongxiang, Wu, Zhiwei, Cao, Wangsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761007/
https://www.ncbi.nlm.nih.gov/pubmed/34874096
http://dx.doi.org/10.1111/acel.13526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761007/
https://www.ncbi.nlm.nih.gov/pubmed/34874096
http://dx.doi.org/10.1111/acel.13526

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