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Inhibition of DNA methyltransferase aberrations reinstates antioxidant aging suppressors and ameliorates renal aging

DNA methylation alterations play mechanistic roles in aging; however, the epigenetic regulators/mediators causally involved in renal aging remain elusive. Here, we report that natural and D‐galactose (D‐gal)‐induced aging kidneys display marked suppression of antiaging factor NRF2 (nuclear factor er...

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Detalles Bibliográficos
Autores principales:	Gao, Qi, Chen, Fang, Zhang, Lijun, Wei, Ai, Wang, Yongxiang, Wu, Zhiwei, Cao, Wangsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761007/ https://www.ncbi.nlm.nih.gov/pubmed/34874096 http://dx.doi.org/10.1111/acel.13526

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