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Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy

The “rejuvenating” effect of growth differentiation factor 11 (GDF11) is called into question recently, and its role, as well as plausible signaling mechanisms in liver senescence, is unclear. To overexpress or knockdown GDF11, aged male mice are injected with a single dose of adeno‐associated virus...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Li, Ying, Yang, Xiao, Dong, Wei, Yang, Jiankun, Hu, Qi, Zhang, Cuntai, Fang, Haoshu, Liu, Anding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761011/
https://www.ncbi.nlm.nih.gov/pubmed/34905649
http://dx.doi.org/10.1111/acel.13532