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Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes

Metformin, the most commonly prescribed anti‐diabetes medication, has multiple reported health benefits, including lowering the risks of cardiovascular disease and cancer, improving cognitive function with age, extending survival in diabetic patients, and, in several animal models, promoting youthfu...

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Detalles Bibliográficos
Autores principales: Onken, Brian, Sedore, Christine A., Coleman‐Hulbert, Anna L., Hall, David, Johnson, Erik, Jones, Eleanor Grace, Banse, Stephen A., Huynh, Phu, Guo, Suzhen, Xue, Jian, Chen, Esteban, Harinath, Girish, Foulger, Anna C., Chao, Elizabeth A., Hope, June, Bhaumik, Dipa, Plummer, Todd, Inman, Delaney, Morshead, Mackenzie, Guo, Max, Lithgow, Gordon J., Phillips, Patrick C., Driscoll, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761014/
https://www.ncbi.nlm.nih.gov/pubmed/34837316
http://dx.doi.org/10.1111/acel.13488