Senescence‐induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics

Aging and senescence impact CD4 T helper cell (Th) subset differentiation during influenza infection. In the lungs of infected aged mice, there were significantly greater percentages of Th cells expressing the transcription factor FoxP3, indicative of regulatory CD4 T cells (Treg), when compared to...

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Detalles Bibliográficos
Autores principales: Lorenzo, Erica C., Torrance, Blake L., Keilich, Spencer R., Al‐Naggar, Iman, Harrison, Andrew, Xu, Ming, Bartley, Jenna M., Haynes, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761018/
https://www.ncbi.nlm.nih.gov/pubmed/34962049
http://dx.doi.org/10.1111/acel.13525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761018/
https://www.ncbi.nlm.nih.gov/pubmed/34962049
http://dx.doi.org/10.1111/acel.13525

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