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Regulatory role of cathepsin L in induction of nuclear laminopathy in Alzheimer’s disease

Experimental and clinical therapies in the field of Alzheimer's disease (AD) have focused on elimination of extracellular amyloid beta aggregates or prevention of cytoplasmic neuronal fibrillary tangles formation, yet these approaches have been generally ineffective. Interruption of nuclear lam...

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Detalles Bibliográficos
Autores principales: Islam, Md Imamul, Nagakannan, Pandian, Shcholok, Tetiana, Contu, Fabio, Mai, Sabine, Albensi, Benedict C, Del Bigio, Marc R., Wang, Jun‐Feng, Sharoar, Md Golam, Yan, Riqiang, Park, Il‐Seon, Eftekharpour, Eftekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761039/
https://www.ncbi.nlm.nih.gov/pubmed/34905652
http://dx.doi.org/10.1111/acel.13531