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Y380Q novel mutation in receptor-binding domain of SARS-CoV-2 spike protein together with C379W interfere in the neutralizing antibodies interaction

We aimed to describe the SARS-CoV-2 lineages circulating early pandemic among samples with S gene dropout and characterize the receptor-binding domain (RBD) of viral spike protein. Adults and children older than 2 months with signs and symptoms of COVID-19 were prospectively enrolled from May to Oct...

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Detalles Bibliográficos
Autores principales: Sartor, Ivaine Tais Sauthier, Varela, Fernanda Hammes, Meireles, Mariana Rost, Kern, Luciane Beatriz, Azevedo, Thaís Raupp, Giannini, Gabriela Luchiari Tumioto, da Silva, Mariana Soares, Demoliner, Meriane, Gularte, Juliana Schons, de Almeida, Paula Rodrigues, Fleck, Juliane Deise, Zavaglia, Gabriela Oliveira, Fernandes, Ingrid Rodrigues, de David, Caroline Nespolo, Santos, Amanda Paz, de Almeida, Walquiria Aparecida Ferreira, Porto, Victor Bertollo Gomes, Scotta, Marcelo Comerlato, Vieira, Gustavo Fioravanti, Spilki, Fernando Rosado, Stein, Renato T., Polese-Bonatto, Márcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761118/
https://www.ncbi.nlm.nih.gov/pubmed/35219552
http://dx.doi.org/10.1016/j.diagmicrobio.2022.115636