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Assigning protein function from domain-function associations using DomFun

BACKGROUND: Protein function prediction remains a key challenge. Domain composition affects protein function. Here we present DomFun, a Ruby gem that uses associations between protein domains and functions, calculated using multiple indices based on tripartite network analysis. These domain-function...

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Detalles Bibliográficos
Autores principales: Rojano, Elena, Jabato, Fernando M., Perkins, James R., Córdoba-Caballero, José, García-Criado, Federico, Sillitoe, Ian, Orengo, Christine, Ranea, Juan A. G., Seoane-Zonjic, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761305/
https://www.ncbi.nlm.nih.gov/pubmed/35033002
http://dx.doi.org/10.1186/s12859-022-04565-6