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Assigning protein function from domain-function associations using DomFun

BACKGROUND: Protein function prediction remains a key challenge. Domain composition affects protein function. Here we present DomFun, a Ruby gem that uses associations between protein domains and functions, calculated using multiple indices based on tripartite network analysis. These domain-function...

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Detalles Bibliográficos
Autores principales:	Rojano, Elena, Jabato, Fernando M., Perkins, James R., Córdoba-Caballero, José, García-Criado, Federico, Sillitoe, Ian, Orengo, Christine, Ranea, Juan A. G., Seoane-Zonjic, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Software
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761305/ https://www.ncbi.nlm.nih.gov/pubmed/35033002 http://dx.doi.org/10.1186/s12859-022-04565-6

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