Securin overexpression correlates with the activated Rb/E2F1 pathway and histone H3 epigenetic modifications in raw areca nut-induced carcinogenesis in mice

BACKGROUND: Raw areca nut (RAN) consumption induces oral, esophageal and gastric cancers, which are significantly associated with the overexpression of pituitary tumor transforming gene 1/securin and chromosomal instability (CIN). An association of Securin/PTTG1 upregulation and gastric cancer in hu...

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Detalles Bibliográficos
Autores principales: Boruah, Nabamita, Singh, Chongtham Sovachandra, Swargiary, Pooja, Dkhar, Hughbert, Chatterjee, Anupam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761315/
https://www.ncbi.nlm.nih.gov/pubmed/35033090
http://dx.doi.org/10.1186/s12935-022-02442-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761315/
https://www.ncbi.nlm.nih.gov/pubmed/35033090
http://dx.doi.org/10.1186/s12935-022-02442-z

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