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Preparation of multiplexed control materials for cancer mutation analysis by genome editing in GM12878 cells

BACKGROUND: Quality control materials are necessary for assay development, test validation, and proficiency testing in cancer mutation analysis. Most of the existing controls for somatic mutations only harbor a single variant and are derived from unstable cell lines. This study aimed to establish a...

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Detalles Bibliográficos
Autores principales: Lin, Guigao, Zhang, Kuo, Han, Yanxi, Peng, Rongxue, Li, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761438/
https://www.ncbi.nlm.nih.gov/pubmed/34811797
http://dx.doi.org/10.1002/jcla.24139