Quantitative detections of TP53 gene mutations improve the diagnosis and prognostic prediction of biliary tract cancers using droplet digital PCR

OBJECTIVE: Biliary tract cancer (BTC) is a rare malignancy and lack of effective diagnostic and prognostic marker. Here, we aimed to investigate the clinical implication of TP53 mutation detection in BTC using droplet digital PCR (ddPCR). METHODS: TP53 gene (loci p.R175H, p.R248Q, p.R248W, and p.R27...

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Detalles Bibliográficos
Autores principales: Xiao, Xiao, Zhou, Jun, Fang, Meng, Ji, Jun, Huang, Chenjun, Du, Fei, Ai, Wenchao, Wang, Ying, Gao, Zhiyuang, Qiu, Zhiquan, Gao, Chunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761443/
https://www.ncbi.nlm.nih.gov/pubmed/34813121
http://dx.doi.org/10.1002/jcla.24103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761443/
https://www.ncbi.nlm.nih.gov/pubmed/34813121
http://dx.doi.org/10.1002/jcla.24103

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