Therapeutic anti-glioma effect of the combined action of PCSK inhibitor with the anti-tumoral factors secreted by Poly (I:C)-stimulated macrophages

Macrophages plasticity is a key feature in cancer progression. Neoplastic cells can alter their immune functions and orient them into a pro-tumoral phenotype. In this context, we developed a new therapeutic strategy to switch macrophages phenotype and reactivate their anti-tumoral functions. We show...

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Detalles Bibliográficos
Autores principales: Rose, Mélanie, Duhamel, Marie, Aboulouard, Soulaimane, Kobeissy, Firas, Tierny, Dominique, Fournier, Isabelle, Rodet, Franck, Salzet, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761570/
https://www.ncbi.nlm.nih.gov/pubmed/33402730
http://dx.doi.org/10.1038/s41417-020-00286-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761570/
https://www.ncbi.nlm.nih.gov/pubmed/33402730
http://dx.doi.org/10.1038/s41417-020-00286-1

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