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CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo

The outcome of prostate cancer (PCa) patients is highly variable and depends on whether or not distant metastases occur. Multiple chromosomal deletions have been linked to early tumor marker PSA recurrence (biochemical relapse, BCR) after radical prostatectomy (RP), but their potential role for dist...

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Detalles Bibliográficos
Autores principales: Oh-Hohenhorst, Su Jung, Tilki, Derya, Ahlers, Ann-Kristin, Suling, Anna, Hahn, Oliver, Tennstedt, Pierre, Matuszcak, Christiane, Maar, Hanna, Labitzky, Vera, Hanika, Sandra, Starzonek, Sarah, Baumgart, Simon, Johnsen, Steven A., Kluth, Martina, Sirma, Hüseyin, Simon, Ronald, Sauter, Guido, Huland, Hartwig, Schumacher, Udo, Lange, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761572/
https://www.ncbi.nlm.nih.gov/pubmed/33414516
http://dx.doi.org/10.1038/s41417-020-00288-z