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Ingestion of hemozoin by peripheral blood mononuclear cells alters temporal gene expression of ubiquitination processes

Plasmodium falciparum (Pf) malaria is among the leading causes of childhood morbidity and mortality worldwide. During a natural infection, ingestion of the malarial parasite product, hemozoin (PfHz), by circulating phagocytic cells induces dysregulation in innate immunity and enhances malaria pathog...

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Detalles Bibliográficos
Autores principales: Anyona, Samuel B., Cheng, Qiuying, Raballah, Evans, Hurwitz, Ivy, Lambert, Christophe G., McMahon, Benjamin H., Ouma, Collins, Perkins, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761598/
https://www.ncbi.nlm.nih.gov/pubmed/35071802
http://dx.doi.org/10.1016/j.bbrep.2022.101207