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Ingestion of hemozoin by peripheral blood mononuclear cells alters temporal gene expression of ubiquitination processes
Plasmodium falciparum (Pf) malaria is among the leading causes of childhood morbidity and mortality worldwide. During a natural infection, ingestion of the malarial parasite product, hemozoin (PfHz), by circulating phagocytic cells induces dysregulation in innate immunity and enhances malaria pathog...
Autores principales: | Anyona, Samuel B., Cheng, Qiuying, Raballah, Evans, Hurwitz, Ivy, Lambert, Christophe G., McMahon, Benjamin H., Ouma, Collins, Perkins, Douglas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761598/ https://www.ncbi.nlm.nih.gov/pubmed/35071802 http://dx.doi.org/10.1016/j.bbrep.2022.101207 |
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