CRISPR/Cas9 disruption of EpCAM Exon 2 results in cell-surface expression of a truncated protein targeted by an EpCAM specific T cell engager

CRISPR/Cas9 gene-editing technology allows researchers to study protein function by specifically introducing double-stranded breaks in the gene of interest then analyze its subsequent loss in sensitive biological assays. To help characterize one of a series of highly potent, conditionally active, T...

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Detalles Bibliográficos
Autores principales: Bagheri, Andisheh, Culp, Patricia A., DuBridge, Robert B., Chen, Tseng-hui Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761601/
https://www.ncbi.nlm.nih.gov/pubmed/35071801
http://dx.doi.org/10.1016/j.bbrep.2022.101205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761601/
https://www.ncbi.nlm.nih.gov/pubmed/35071801
http://dx.doi.org/10.1016/j.bbrep.2022.101205

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