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Mediator Complex Subunit 19 Promotes the Development of Hepatocellular Carcinoma by Regulating the AKT/mTOR Signaling Pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, the pathogenesis of which remains unclear. Mediator complex subunit 19 (MED19), a subunit of the Mediator complex, is a multi-protein co-activator necessary for DNA transcription factors to induce RNA polymerase I...

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Detalles Bibliográficos
Autores principales: Zhang, Yuting, Qin, Peifang, Xu, Xingfeng, Li, Mao, Huang, Haitao, Yan, Jianguo, Zhou, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761619/
https://www.ncbi.nlm.nih.gov/pubmed/35047403
http://dx.doi.org/10.3389/fonc.2021.792285