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Characterization of the Population Pharmacokinetics of Moxidectin in Adults Infected with Strongyloides Stercoralis: Support for a Fixed-Dose Treatment Regimen

BACKGROUND: Moxidectin has recently attracted attention as a novel candidate for the treatment of helminth infections, including Strongyloides stercoralis. This study aims to characterize the population pharmacokinetics (PPK) of moxidectin in S. stercoralis-infected adults using a pharmacometric app...

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Detalles Bibliográficos
Autores principales: Smit, Cornelis, Hofmann, Daniela, Sayasone, Somphou, Keiser, Jennifer, Pfister, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761718/
https://www.ncbi.nlm.nih.gov/pubmed/34296417
http://dx.doi.org/10.1007/s40262-021-01048-4