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Modulation of IL-6 Expression by KLF4-Mediated Transactivation and PCAF-Mediated Acetylation in Sublytic C5b-9-Induced Rat Glomerular Mesangial Cells

Interleukin-6 (IL-6) overproduction has been considered to contribute to inflammatory damage of glomerular mesangial cells (GMCs) in human mesangial proliferative glomerulonephritis (MsPGN) and its rat model called Thy-1 nephritis (Thy-1N). However, the regulatory mechanisms of IL-6 expression in GM...

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Detalles Bibliográficos
Autores principales: Xia, Lu, Liu, Yu, Zhang, Zhiwei, Gong, Yajuan, Yu, Tianyi, Zhao, Dan, Qiu, Wen, Wang, Yingwei, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761757/
https://www.ncbi.nlm.nih.gov/pubmed/35046941
http://dx.doi.org/10.3389/fimmu.2021.779667