Spatial and Temporal Heterogeneity of Tumor-Infiltrating Lymphocytes in Advanced Urothelial Cancer

Checkpoint inhibitors targeting PD-(L)1 induce objective responses in 20% of patients with metastatic urothelial cancer (UC). CD8(+) T cell infiltration has been proposed as a putative biomarker for response to checkpoint inhibitors. Nevertheless, data on spatial and temporal heterogeneity of tumor-...

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Detalles Bibliográficos
Autores principales: van Wilpe, Sandra, Gorris, Mark A. J., van der Woude, Lieke L., Sultan, Shabaz, Koornstra, Rutger H. T., van der Heijden, Antoine G., Gerritsen, Winald R., Simons, Michiel, de Vries, I. Jolanda M., Mehra, Niven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761759/
https://www.ncbi.nlm.nih.gov/pubmed/35046958
http://dx.doi.org/10.3389/fimmu.2021.802877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761759/
https://www.ncbi.nlm.nih.gov/pubmed/35046958
http://dx.doi.org/10.3389/fimmu.2021.802877

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