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Multiomic Metabolic Enrichment Network Analysis Reveals Metabolite–Protein Physical Interaction Subnetworks Altered in Cancer

Metabolism is recognized as an important driver of cancer progression and other complex diseases, but global metabolite profiling remains a challenge. Protein expression profiling is often a poor proxy since existing pathway enrichment models provide an incomplete mapping between the proteome and me...

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Detalles Bibliográficos
Autores principales: Blum, Benjamin C., Lin, Weiwei, Lawton, Matthew L., Liu, Qian, Kwan, Julian, Turcinovic, Isabella, Hekman, Ryan, Hu, Pingzhao, Emili, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761777/
https://www.ncbi.nlm.nih.gov/pubmed/34933084
http://dx.doi.org/10.1016/j.mcpro.2021.100189