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O-Acetyl-GD2 as a Therapeutic Target for Breast Cancer Stem Cells

SYNOPSIS: A sugar-lipid molecule called OAcGD2 is a novel marker for breast cancer stem cells. Treatment with anti-OAcGD2 mAb8B6 may have superior anticancer efficacy by targeting cancer stem cells, thereby reducing metastasis and recurrence of cancer. BACKGROUND: Cancer stem cells (CSCs) that drive...

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Detalles Bibliográficos
Autores principales: Cheng, Jing-Yan, Hung, Jung-Tung, Lin, Juway, Lo, Fei-Yun, Huang, Jing-Rong, Chiou, Shih-Pin, Wang, Ya-Hui, Lin, Ruey-Jen, Wu, Jen-Chine, Yu, John, Yu, Alice L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761789/
https://www.ncbi.nlm.nih.gov/pubmed/35046949
http://dx.doi.org/10.3389/fimmu.2021.791551