Grass Carp (Ctenopharyngodon idella) KAT8 Inhibits IFN 1 Response Through Acetylating IRF3/IRF7

Post-translational modifications (PTMs), such as phosphorylation and ubiquitination, etc., have been reported to modulate the activities of IRF3 and IRF7. In this study, we found an acetyltransferase KAT8 in grass carp (CiKAT8, MW286472) that acetylated IRF3/IRF7 and then resulted in inhibition of I...

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Detalles Bibliográficos
Autores principales: Li, Meifeng, Hu, Jihuan, Mao, Huiling, Li, Dongming, Jiang, Zeyin, Sun, Zhichao, Yu, Tingting, Hu, Chengyu, Xu, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761793/
https://www.ncbi.nlm.nih.gov/pubmed/35046960
http://dx.doi.org/10.3389/fimmu.2021.808159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761793/
https://www.ncbi.nlm.nih.gov/pubmed/35046960
http://dx.doi.org/10.3389/fimmu.2021.808159

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