B Cell Receptor Signaling and Protein Kinase D2 Support Regulatory B Cell Function in Pancreatic Cancer

B cells can act as potent suppressors of anti-tumor T cell immunity, presenting a mechanism of resistance to immunotherapy. In pancreatic ductal adenocarcinoma, B cells can display a T cell-suppressive or regulatory phenotype centered on the expression of the cytokine Interleukin 35 (IL-35). While B...

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Detalles Bibliográficos
Autores principales: Michaud, Daniel, Mirlekar, Bhalchandra, Steward, Colleen, Bishop, Gail, Pylayeva-Gupta, Yuliya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761795/
https://www.ncbi.nlm.nih.gov/pubmed/35046933
http://dx.doi.org/10.3389/fimmu.2021.745873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761795/
https://www.ncbi.nlm.nih.gov/pubmed/35046933
http://dx.doi.org/10.3389/fimmu.2021.745873

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