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Preclinical and exploratory human studies of novel (68)Ga-labeled D-peptide antagonist for PET imaging of TIGIT expression in cancers

PURPOSE: While TIGIT has been propelled as a next-generation target in cancer immunotherapy, anti-TIGIT therapy seems to be promising for a fraction of patients in clinical trials. Therefore, patient stratification is critical for this therapy, which could benefit from a whole-body, non-invasive, an...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobo, Zhou, Ming, Chen, Bei, Liu, Huanhuan, Fang, Jianyang, Xiang, Shijun, Hu, Shuo, Zhang, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761874/
https://www.ncbi.nlm.nih.gov/pubmed/35037984
http://dx.doi.org/10.1007/s00259-021-05672-x