Cargando…

Preclinical and exploratory human studies of novel (68)Ga-labeled D-peptide antagonist for PET imaging of TIGIT expression in cancers

PURPOSE: While TIGIT has been propelled as a next-generation target in cancer immunotherapy, anti-TIGIT therapy seems to be promising for a fraction of patients in clinical trials. Therefore, patient stratification is critical for this therapy, which could benefit from a whole-body, non-invasive, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xiaobo, Zhou, Ming, Chen, Bei, Liu, Huanhuan, Fang, Jianyang, Xiang, Shijun, Hu, Shuo, Zhang, Xianzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761874/ https://www.ncbi.nlm.nih.gov/pubmed/35037984 http://dx.doi.org/10.1007/s00259-021-05672-x

Ejemplares similares

Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of (68)Ga-Labeled FAPI Dimer
por: Zhao, Liang, et al.
Publicado: (2022)

(68)Ga-Labeled Maleimide for Blood Pool and Lymph PET Imaging through Covalent Bonding to Serum Albumin In Vivo
por: Feng, Lixia, et al.
Publicado: (2022)

Synthesis, preclinical evaluation and radiation dosimetry of a dual targeting PET tracer [(68)Ga]Ga-FAPI-RGD
por: Zang, Jie, et al.
Publicado: (2022)

Preclinical Melanoma Imaging with (68)Ga-Labeled α-Melanocyte-Stimulating Hormone Derivatives Using PET
por: Zhang, Chengcheng, et al.
Publicado: (2017)

PET Imaging of FSHR Expression in Tumors with (68)Ga-Labeled FSH1 Peptide
por: Pan, Donghui, et al.
Publicado: (2017)

Peptide-Based [(68)Ga]Ga Labeled PET Tracer for Tumor Imaging by Targeting Tumor-Associated Macrophages
por: Huang, Mingxing, et al.
Publicado: (2022)

Site-specific (68)Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models
por: Dewulf, Jonatan, et al.
Publicado: (2023)

Preclinical PET and MR Evaluation of (89)Zr- and (68)Ga-Labeled Nanodiamonds in Mice over Different Time Scales
por: Winter, Gordon, et al.
Publicado: (2022)

Preclinical evaluation of [(68)Ga]NOTA-pentixafor for PET imaging of CXCR4 expression in vivo — a comparison to [(68)Ga]pentixafor
por: Poschenrieder, Andreas, et al.
Publicado: (2016)

(68)Ga-Labeled Cyclic NGR Peptide for MicroPET Imaging of CD13 Receptor Expression
por: Shao, Yahui, et al.
Publicado: (2014)

Multifarious Ga-68 Labeled PET Radiopharmaceuticals in Imaging Various Malignancies
por: Vatsa, Rakhee, et al.
Publicado: (2018)

PET imaging of PARP expression using (68)Ga-labelled inhibitors
por: Wang, Xiangwei, et al.
Publicado: (2023)

Gastrin-releasing Peptide Receptor Imaging in Breast Cancer Using the Receptor Antagonist (68)Ga-RM2 And PET
por: Stoykow, Christian, et al.
Publicado: (2016)

Radiopharmaceutical Formulation and Preclinical Testing of (68)Ga-Labeled DOTA-MGS5 for the Regulatory Approval of a First Exploratory Clinical Trial
por: Hörmann, Anton A., et al.
Publicado: (2021)

Automated GMP Production and Preclinical Evaluation of [(68)Ga]Ga-TEoS-DAZA and [(68)Ga]Ga-TMoS-DAZA
por: Greiser, Julia, et al.
Publicado: (2022)

Evaluation of (68)Ga-Radiolabeled Peptides for HER2 PET Imaging
por: Ducharme, Maxwell, et al.
Publicado: (2022)

Development of (68)Ga-labelled ultrasound microbubbles for whole-body PET imaging
por: Hernández-Gil, Javier, et al.
Publicado: (2019)

Peptide-based PET imaging agent of tumor TIGIT expression
por: Weng, Dinghu, et al.
Publicado: (2023)

Radiosynthesis and preclinical evaluation of [(68)Ga]Ga-NOTA-folate for PET imaging of folate receptor β-positive macrophages
por: Moisio, Olli, et al.
Publicado: (2020)

[(68)Ga]Ga-DOTA-TOC: The First FDA-Approved (68)Ga-Radiopharmaceutical for PET Imaging
por: Hennrich, Ute, et al.
Publicado: (2020)

The effects of novel macrocyclic chelates on the targeting properties of the (68)Ga-labeled Gastrin releasing peptide receptor antagonist RM2
por: Wang, Yinwen, et al.
Publicado: (2023)

PET imaging with [(68)Ga]-labeled TGFβ-targeting peptide in a mouse PANC-1 tumor model
por: Li, Yong, et al.
Publicado: (2023)

Gastrin-Releasing Peptide Receptor Antagonist [(68)Ga]RM2 PET/CT for Staging of Pre-Treated, Metastasized Breast Cancer
por: Michalski, Kerstin, et al.
Publicado: (2021)

Highly variable biodistribution of (68)Ga labeled somatostatin analogues (68)Ga-DOTA-NOC and (68)Ga-DOTA-TATE in neuroendocrine tumors: clinical implications for somatostatin receptor directed PET/CT
por: Cheng, Monica, et al.
Publicado: (2022)

(68)Ga-labelled exendin-3, a new agent for the detection of insulinomas with PET
por: Brom, Maarten, et al.
Publicado: (2010)

pH-Responsive Carboxymethylcellulose Nanoparticles for (68)Ga-WBC Labeling in PET Imaging
por: Piras, Anna Maria, et al.
Publicado: (2019)

Recent Advances of (68)Ga-Labeled PET Radiotracers with Nitroimidazole in the Diagnosis of Hypoxia Tumors
por: Nguyen, Anh Thu, et al.
Publicado: (2023)

Dual targeting PET tracer [(68)Ga]Ga-FAPI-RGD in patients with lung neoplasms: a pilot exploratory study
por: Wang, Rongxi, et al.
Publicado: (2023)

Radiochemistry and Preclinical PET Imaging of (68)Ga-Desferrioxamine Radiotracers Targeting Prostate-Specific Membrane Antigen
por: Gourni, Eleni, et al.
Publicado: (2017)

Image quality analysis of (44)Sc on two preclinical PET scanners: a comparison to (68)Ga
por: Rosar, Florian, et al.
Publicado: (2020)

Twins in spirit - episode I: comparative preclinical evaluation of [(68)Ga]DOTATATE and [(68)Ga]HA-DOTATATE
por: Schottelius, Margret, et al.
Publicado: (2015)

[(68)Ga]Ga-PSMA-11: The First FDA-Approved (68)Ga-Radiopharmaceutical for PET Imaging of Prostate Cancer
por: Hennrich, Ute, et al.
Publicado: (2021)

Prevalence of Brain Incidental Lesions Detected by (68)Ga-DOTA Peptides PET/CT
por: Albano, Domenico, et al.
Publicado: (2022)

Novel Preclinical and Radiopharmaceutical Aspects of [(68)Ga]Ga-PSMA-HBED-CC: A New PET Tracer for Imaging of Prostate Cancer
por: Eder, Matthias, et al.
Publicado: (2014)

PET Probes for Preclinical Imaging of GRPR-Positive Prostate Cancer: Comparative Preclinical Study of [(68)Ga]Ga-NODAGA-AMBA and [(44)Sc]Sc-NODAGA-AMBA
por: Kálmán-Szabó, Ibolya, et al.
Publicado: (2022)

Synthesis of (68)Ga-Labeled cNGR-Based Glycopeptides and In Vivo Evaluation by PET Imaging
por: Gyuricza, Barbara, et al.
Publicado: (2021)

Optimized (68)Ga-Labeled Urea-Based PSMA-Targeted PET Tracers for Prostate Cancer
por: Wu, Yitian, et al.
Publicado: (2022)

(68)Ga-labeled amphiphilic polymer nanoparticles for PET imaging of sentinel lymph node metastasis
por: Chen, Qin, et al.
Publicado: (2023)

Voxel-based comparison of [(68)Ga]Ga-RM2-PET/CT and [(68)Ga]Ga-PSMA-11-PET/CT with histopathology for diagnosis of primary prostate cancer
por: Fassbender, Thomas Franz, et al.
Publicado: (2020)

PET imaging of α(v)β(3) integrin expression in tumours with (68)Ga-labelled mono-, di- and tetrameric RGD peptides
por: Dijkgraaf, Ingrid, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ic4ufnbncoij6moq05ck9oare8