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Adenosine A(2A) Receptor in Bone Marrow-Derived Cells Mediated Macrophages M2 Polarization via PPARγ-P65 Pathway in Chronic Hypoperfusion Situation

Background: The role of adenosine A(2A) receptor (A(2A)R) in the ischemic white matter damage induced by chronic cerebral hypoperfusion remains obscure. Here we investigated the role of A(2A)R in the process of macrophage polarizations in the white matter damage induced by chronic cerebral hypoperfu...

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Detalles Bibliográficos
Autores principales: Mou, Ke-Jie, Shen, Kai-Feng, Li, Yan-Ling, Wu, Zhi-Feng, Duan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761901/
https://www.ncbi.nlm.nih.gov/pubmed/35046793
http://dx.doi.org/10.3389/fnagi.2021.792733