Superior infectivity of the fiber chimeric oncolytic adenoviruses Ad5/35 and Ad5/3 over Ad5-delta-24-RGD in primary glioma cultures

Ad5-delta-24-RGD is currently the most clinically advanced recombinant adenovirus (rAd) for glioma therapy. We constructed a panel of fiber-modified rAds (Ad5RGD, Ad5/3, Ad5/35, Ad5/3RGD, and Ad5/35RGD, all harboring the delta-24 modification) and compared their infectivity, replication, reproductio...

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Detalles Bibliográficos
Autores principales: Stepanenko, Aleksei A., Sosnovtseva, Anastasiia O., Valikhov, Marat P., Chernysheva, Anastasia A., Cherepanov, Sergey A., Yusubalieva, Gaukhar M., Ruzsics, Zsolt, Lipatova, Anastasiia V., Chekhonin, Vladimir P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761956/
https://www.ncbi.nlm.nih.gov/pubmed/35071746
http://dx.doi.org/10.1016/j.omto.2021.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761956/
https://www.ncbi.nlm.nih.gov/pubmed/35071746
http://dx.doi.org/10.1016/j.omto.2021.12.013

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