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Genomic evolution and diverse models of systemic metastases in colorectal cancer

OBJECTIVE: The systemic spread of colorectal cancer (CRC) is dominated by the portal system and exhibits diverse patterns of metastasis without systematical genomic investigation. Here, we evaluated the genomic evolution of CRC with multiorgan metastases using multiregion sequencing. DESIGN: Whole-e...

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Detalles Bibliográficos
Autores principales: Chen, Hai-Ning, Shu, Yang, Liao, Fei, Liao, Xue, Zhang, Hongying, Qin, Yun, Wang, Zhu, Luo, Maochao, Liu, Qiuluo, Xue, Zhinan, Cao, Minyuan, Zhang, Shouyue, Zhang, Wei-Han, Hou, Qianqian, Xia, Xuyang, Luo, Han, Zhang, Yan, Yang, Lie, Hu, Jian-Kun, Fu, Xianghui, Liu, Bo, Hu, Hongbo, Huang, Canhua, Peng, Yong, Cheng, Wei, Dai, Lunzhi, Yang, Li, Zhang, Wei, Dong, Biao, Li, Yuan, Wei, Yuquan, Xu, Heng, Zhou, Zong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762014/
https://www.ncbi.nlm.nih.gov/pubmed/33632712
http://dx.doi.org/10.1136/gutjnl-2020-323703